Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E(2) release via C/EBPβ in human bronchial epithelial cells

We have demonstrated that LPA (lysophosphatidic acid)-induced IL (interleukin)-8 secretion was partly mediated via transactivation of EGFR [EGF (epidermal growth factor) receptor] in HBEpCs (human bronchial epithelial primary cells). The present study provides evidence that LPA-induced transactivati...

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Bibliographische Detailangaben
Hauptverfasser: HE, Donghong, NATARAJAN, Viswanathan, STERN, Randi, GORSHKOVA, Irina A., SOLWAY, Julian, SPANNHAKE, Ernst Wm., ZHAO, Yutong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659593/
https://ncbi.nlm.nih.gov/pubmed/18294142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071649
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