AMP-Activated Protein Kinase Deficiency Enhances Myocardial Ischemia/Reperfusion Injury but Has Minimal Effect on the Antioxidant/Antinitrative Protection of Adiponectin

BACKGROUND: Diabetes increases the morbidity/mortality of ischemic heart disease, but the underlying mechanisms are incompletely understood. Deficiency of both AMP-activated protein kinase (AMPK) and adiponectin occurs in diabetes, but whether AMPK is cardioprotective or a central mediator of adipon...

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Autori principali: Wang, Yajing, Gao, Erhe, Tao, Ling, Lau, Wayne Bond, Yuan, Yuexin, Goldstein, Barry J., Lopez, Bernard L., Christopher, Theodore A., Tian, Rong, Koch, Walter, Ma, Xin-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658653/
https://ncbi.nlm.nih.gov/pubmed/19188503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.815043
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