Phase I Study of Adenovirus p53 Administered by Bronchoalveolar Lavage in Patients With Bronchioloalveolar Cell Lung Carcinoma: ECOG 6597

PURPOSE: This pilot phase I trial evaluated the safety and maximum-tolerated dose of p53 gene transfer using an adenovirus vector (Ad-p53) delivered via bronchoalveolar lavage (BAL) to patients with bronchioloalveolar lung carcinoma (BAC). PATIENTS AND METHODS: Patients were initially administered t...

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Hlavní autoři: Keedy, Vicki, Wang, Wei, Schiller, Joan, Chada, Sunil, Slovis, Bonnie, Coffee, Keith, Worrell, John, Thet, Lyn A., Johnson, David H., Carbone, David P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2008
Témata:
Phase I and Clinical Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654378/
https://ncbi.nlm.nih.gov/pubmed/18757331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.15.6927
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