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Brief exposure to hyperoxia depletes the glial progenitor pool and impairs functional recovery after hypoxic-ischemic brain injury

Patterns of hypoxic-ischemic brain injury in infants and children suggest vulnerability in regions of white matter development, and injured patients develop defects in myelination resulting in cerebral palsy and motor deficits. Reperfusion exacerbates the oxidative stress that occurs after such inju...

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Détails bibliographiques
Auteurs principaux: Koch, Joshua D, Miles, Darryl K, Gilley, Jennifer A, Yang, Cui-Ping, Kernie, Steven G
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652354/
https://ncbi.nlm.nih.gov/pubmed/18334993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.15
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