A missense variant (P10L) of the melanopsin (Opn4) gene is associated with Seasonal Affective Disorder

BACKGROUND: Melanopsin, a non-visual photopigment, may play a role in aberrant responses to low winter light levels in Seasonal Affective Disorder (SAD). We hypothesized that functional sequence variation in the melanopsin gene (Opn4) could contribute to increasing the light needed for normal functi...

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Auteurs principaux: Roecklein, Kathryn A., Rohan, Kelly J., Duncan, Wallace C., Rollag, Mark D., Rosenthal, Norman E., Lipsky, Robert H., Provencio, Ignacio
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647333/
https://ncbi.nlm.nih.gov/pubmed/18804284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2008.08.005
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