Green Tea Polyphenols Rescue of Brain Defects Induced by Overexpression of DYRK1A

Individuals with partial HSA21 trisomies and mice with partial MMU16 trisomies containing an extra copy of the DYRK1A gene present various alterations in brain morphogenesis. They present also learning impairments modeling those encountered in Down syndrome. Previous MRI and histological analyses of...

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Main Authors: Guedj, Fayçal, Sébrié, Catherine, Rivals, Isabelle, Ledru, Aurelie, Paly, Evelyne, Bizot, Jean C., Smith, Desmond, Rubin, Edward, Gillet, Brigitte, Arbones, Mariona, Delabar, Jean M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645681/
https://ncbi.nlm.nih.gov/pubmed/19242551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004606
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