Green Tea Polyphenols Rescue of Brain Defects Induced by Overexpression of DYRK1A

Individuals with partial HSA21 trisomies and mice with partial MMU16 trisomies containing an extra copy of the DYRK1A gene present various alterations in brain morphogenesis. They present also learning impairments modeling those encountered in Down syndrome. Previous MRI and histological analyses of...

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Autors principals: Guedj, Fayçal, Sébrié, Catherine, Rivals, Isabelle, Ledru, Aurelie, Paly, Evelyne, Bizot, Jean C., Smith, Desmond, Rubin, Edward, Gillet, Brigitte, Arbones, Mariona, Delabar, Jean M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645681/
https://ncbi.nlm.nih.gov/pubmed/19242551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004606
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