Uncoupling GP1 and GP2 expression in the Lassa virus glycoprotein complex: implications for GP1 ectodomain shedding

BACKGROUND: Sera from convalescent Lassa fever patients often contains antibodies to Lassa virus (LASV) glycoprotein 1 (GP1), and glycoprotein 2 (GP2); Immunization of non-human primates with viral vectors expressing the arenaviral glycoprotein complex (GPC) confers full protective immunity against...

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Autori principali: Illick, Megan M, Branco, Luis M, Fair, Joseph N, Illick, Kerry A, Matschiner, Alex, Schoepp, Randal, Garry, Robert F, Guttieri, Mary C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645378/
https://ncbi.nlm.nih.gov/pubmed/19105844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-161
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