CRAF Autophosphorylation of Serine 621 Is Required to Prevent Its Proteasome-Mediated Degradation

The CRAF protein kinase regulates proliferative, differentiation, and survival signals from activated RAS proteins to downstream effectors, most often by inducing MEK/ERK activation. A well-established model of CRAF regulation involves RAS-mediated translocation of CRAF to the plasma membrane, where...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Noble, Catherine, Mercer, Kathryn, Hussain, Jahan, Carragher, Linda, Giblett, Susan, Hayward, Robert, Patterson, Cam, Marais, Richard, Pritchard, Catrin A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640467/
https://ncbi.nlm.nih.gov/pubmed/18922468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.08.026
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia