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Glycosynthases Enable a Highly Efficient Chemoenzymatic Synthesis of N-Glycoproteins Carrying Intact Natural N-Glycans

Homogeneous N-glycoproteins carrying defined natural N-glycans are essential for detailed structural and functional studies. The transglycosylation activity of the endo-β-N-acetylglucosaminidases from Arthrobacter protophormiae (Endo-A) and Mucor hiemalis (Endo-M) holds a great potential for glycopr...

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Bibliographic Details
Main Authors: Huang, Wei, Li, Cishan, Li, Bing, Umekawa, Midori, Yamamoto, Kenji, Zhang, Xinyu, Wang, Lai-Xi
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640449/
https://ncbi.nlm.nih.gov/pubmed/19199609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8074677
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