Topical WIN55212-2 Alleviates Intraocular Hypertension in Rats Through a CB1 Receptor-Mediated Mechanism of Action

INTRODUCTION: Systemically administered cannabinoids can reduce intraocular pressure (IOP), but produce undesirable cardiovascular and central nervous system effects. In a chronic model of ocular hypertension, we examined the efficacy of acute topical administration of WIN55212-2 (WIN) in a novel co...

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Auteurs principaux: Oltmanns, Matt H., Samudre, Sandeep S., Castillo, Ivan G., Hosseini, Alireza, Lichtman, Aron H., Allen, Robert C., Lattanzio, Frank A., Williams, Patricia B.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637200/
https://ncbi.nlm.nih.gov/pubmed/18201139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2007.0074
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