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Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria
gC1qR is one of the C1q receptors implicated in the regulation of innate and adaptive immunity. We found that gC1qR inhibits RIG-I and MDA5-dependent antiviral signaling. Double stranded RNA and virus trigger the translocation of gC1qR to the mitochondrial outer membrane leading to the interaction o...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635802/ https://ncbi.nlm.nih.gov/pubmed/19164550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811029106 |
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