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Inhibitors of Cytochrome c Release with Therapeutic Potential for Huntington's Disease

Release of mitochondrial cytochrome c resulting in downstream activation of cell death pathways has been suggested to play a role in neurologic diseases featuring cell death. However, the specific biologic importance of cytochrome c release has not been demonstrated in Huntington's disease (HD)...

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Autors principals: Wang, Xin, Zhu, Shan, Pei, Zhijuan, Drozda, Martin, Stavrovskaya, Irina G., Del Signore, Steven J., Cormier, Kerry, Shimony, Ethan M., Wang, Hongyan, Ferrante, Robert J., Kristal, Bruce S., Friedlander, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632939/
https://ncbi.nlm.nih.gov/pubmed/18799679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1867-08.2008
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