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The effect of alternative permutation testing strategies on the performance of multifactor dimensionality reduction

BACKGROUND: Multifactor Dimensionality Reduction (MDR) is a novel method developed to detect gene-gene interactions in case-control association analysis by exhaustively searching multi-locus combinations. While the end-goal of analysis is hypothesis generation, significance testing is employed to in...

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Bibliographic Details
Main Author: Motsinger-Reif, Alison A
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631601/
https://ncbi.nlm.nih.gov/pubmed/19116021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-1-139
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