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Long-lived Indy induces reduced mitochondrial reactive oxygen species production and oxidative damage
Decreased Indy activity extends lifespan in D. melanogaster without significant reduction in fecundity, metabolic rate, or locomotion. To understand the underlying mechanisms leading to lifespan extension in this mutant strain, we compared the genome-wide gene expression changes in the head and thor...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629441/ https://ncbi.nlm.nih.gov/pubmed/19164521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812484106 |
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