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Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways
BACKGROUND: Pericyte loss is a cardinal feature of early diabetic retinopathy. We previously reported that highly oxidized-glycated low density lipoprotein (HOG-LDL) induces pericyte apoptosis in vitro. In this study, we investigated the role of the mitogen-activated protein kinase (MAPK) signaling...
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Huvudupphovsmän: | , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Molecular Vision
2009
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628314/ https://ncbi.nlm.nih.gov/pubmed/19158958 |
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