Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways

BACKGROUND: Pericyte loss is a cardinal feature of early diabetic retinopathy. We previously reported that highly oxidized-glycated low density lipoprotein (HOG-LDL) induces pericyte apoptosis in vitro. In this study, we investigated the role of the mitogen-activated protein kinase (MAPK) signaling...

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Autori principali: Diffley, J. Matthew, Wu, Mingyuan, Sohn, Mimi, Song, Weiwei, Hammad, Samar M., Lyons, Timothy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Vision 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628314/
https://ncbi.nlm.nih.gov/pubmed/19158958
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