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Carbon-Hydrogen Bond Functionalization Approach for the Synthesis of Fluorenones and ortho-Arylated Benzonitriles

A palladium-catalyzed benzamide ortho-arylation/reaction with (CF(3)CO)(2)O sequence was developed allowing a convenient one-pot synthesis of ortho-arylated benzonitriles and fluorenone derivatives. The outcome of this transformation is dependent on the amide N-alkyl substituent. Dehydration of orth...

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Main Authors: Shabashov, Dmitry, Molina Maldonado, Jesús R., Daugulis, Olafs
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627405/
https://ncbi.nlm.nih.gov/pubmed/18763824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo801300y
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