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TRBP Control of PACT-Induced Phosphorylation of Protein Kinase R Is Reversed by Stress
The TAR RNA binding Protein, TRBP, inhibits the activity of the interferon-induced protein kinase R (PKR), whereas the PKR activator, PACT, activates its function. TRBP and PACT also bind to each other through their double-stranded RNA binding domains (dsRBDs) and their Medipal domains, which may in...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612476/ https://ncbi.nlm.nih.gov/pubmed/18936160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01030-08 |
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