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TRBP Control of PACT-Induced Phosphorylation of Protein Kinase R Is Reversed by Stress

The TAR RNA binding Protein, TRBP, inhibits the activity of the interferon-induced protein kinase R (PKR), whereas the PKR activator, PACT, activates its function. TRBP and PACT also bind to each other through their double-stranded RNA binding domains (dsRBDs) and their Medipal domains, which may in...

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Detalhes bibliográficos
Main Authors: Daher, Aïcha, Laraki, Ghislaine, Singh, Madhurima, Melendez-Peña, Carlos E., Bannwarth, Sylvie, Peters, Antoine H. F. M., Meurs, Eliane F., Braun, Robert E., Patel, Rekha C., Gatignol, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612476/
https://ncbi.nlm.nih.gov/pubmed/18936160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01030-08
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