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Effect of γ-Synuclein Silencing on Apoptotic Pathways in Retinal Ganglion Cells

γ-Synuclein (Syn G) is highly expressed in retinal ganglion cells and the loss of these cells in glaucoma is associated with significant reduction of the intracellular Syn G level. However, a causative relationship between these two events has not been established. Here we show that the knockdown of...

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Autors principals: Surgucheva, Irina, Shestopalov, Valery I., Surguchov, Andrei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606004/
https://ncbi.nlm.nih.gov/pubmed/18936092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806660200
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