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Failure to upregulate the adenosine(2A) receptor-epoxyeicosatrienoic acid pathway contributes to the development of hypertension in Dahl salt-sensitive rats

Adenosine-activated renovascular dilatation in Sprague-Dawley (SD) rats is mediated by stimulating adenosine(2A) receptors (A(2A)R), which is linked to epoxyeicosatrienoic acid (EET) synthesis. The A(2A)R-EET pathway is upregulated by high salt (HS) intake in normotensive SD rats. Because this pathw...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liclican, Elvira L., McGiff, John C., Falck, John R., Carroll, Mairéad A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604823/
https://ncbi.nlm.nih.gov/pubmed/18829737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90502.2008
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