A DNA transposon-based approach to validate oncogenic mutations in the mouse

Large-scale cancer genome projects will soon be able to sequence many cancer genomes to comprehensively identify genetic changes in human cancer. Genome-wide association studies have also identified putative cancer associated loci. Functional validation of these genetic mutations in vivo is becoming...

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Dettagli Bibliografici
Autori principali: Su, Qin, Prosser, Haydn M., Campos, Lia S., Ortiz, Mariaestela, Nakamura, Takuro, Warren, Madhuri, Dupuy, Adam J., Jenkins, Nancy A., Copeland, Neal G., Bradley, Allan, Liu, Pentao
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597691/
https://ncbi.nlm.nih.gov/pubmed/19064922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807785105
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