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Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?

Cellular activation, proliferation and survival in chronic inflammatory diseases is regulated not only by engagement of signal trans-duction pathways that modulate transcription factors required for these processes, but also by epigenetic regulation of transcription factor access to gene promoter re...

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Main Authors: Grabiec, Aleksander M, Tak, Paul P, Reedquist, Kris A
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592777/
https://ncbi.nlm.nih.gov/pubmed/18983693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2489
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