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Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?
Cellular activation, proliferation and survival in chronic inflammatory diseases is regulated not only by engagement of signal trans-duction pathways that modulate transcription factors required for these processes, but also by epigenetic regulation of transcription factor access to gene promoter re...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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BioMed Central
2008
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592777/ https://ncbi.nlm.nih.gov/pubmed/18983693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2489 |
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