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The Vibrio cholerae cytolysin (VCC) promotes activation of mast cell (T helper 2) cytokine production

Many strains of Vibrio cholerae produce a cytolysin (VCC) that forms oligomeric transmembrane pores responsible for vacuolization of several cell types in culture. Here we report that VCC is a TLR2 agonist able to stimulate mast cells to produce several cytokines (IL-4 included) which could contribu...

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Bibliographic Details
Main Authors: Arcidiacono, Diletta, Odom, Sandra, Frossi, Barbara, Rivera, Juan, Paccani, Silvia Rossi, Baldari, Cosima T., Pucillo, Carlo, Montecucco, Cesare, de Bernard, Marina
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590497/
https://ncbi.nlm.nih.gov/pubmed/18005391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2007.01092.x
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