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Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea
Sox2 is a high-mobility transcription factor that is one of the earliest markers of developing inner ear prosensory domains. In humans, mutations in SOX2 cause sensorineural hearing loss and a loss of function study in mice showed that Sox2 is required for prosensory formation in the cochlea. Howeve...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587543/ https://ncbi.nlm.nih.gov/pubmed/19011097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808175105 |
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