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Placental transfer and fetal elimination of morphine-3-β-glucuronide in the pregnant baboon

The glucuronide metabolites of several widely used drugs are detected in fetal plasma following maternal drug administration. However, the disposition of these metabolites is poorly understood and clinical concerns have been raised about accumulation of active metabolites in the fetus. For this reas...

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Autors principals: Garland, Marianne, Abildskov, Kirsten M., Kiu, Tung-wah, Daniel, Salha S., Weldy, Piper, Stark, Raymond I.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587090/
https://ncbi.nlm.nih.gov/pubmed/18566040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.021352
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