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Placental transfer and fetal elimination of morphine-3-β-glucuronide in the pregnant baboon

The glucuronide metabolites of several widely used drugs are detected in fetal plasma following maternal drug administration. However, the disposition of these metabolites is poorly understood and clinical concerns have been raised about accumulation of active metabolites in the fetus. For this reas...

詳細記述

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書誌詳細
主要な著者: Garland, Marianne, Abildskov, Kirsten M., Kiu, Tung-wah, Daniel, Salha S., Weldy, Piper, Stark, Raymond I.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587090/
https://ncbi.nlm.nih.gov/pubmed/18566040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.021352
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