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Placental transfer and fetal elimination of morphine-3-β-glucuronide in the pregnant baboon

The glucuronide metabolites of several widely used drugs are detected in fetal plasma following maternal drug administration. However, the disposition of these metabolites is poorly understood and clinical concerns have been raised about accumulation of active metabolites in the fetus. For this reas...

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Détails bibliographiques
Auteurs principaux: Garland, Marianne, Abildskov, Kirsten M., Kiu, Tung-wah, Daniel, Salha S., Weldy, Piper, Stark, Raymond I.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587090/
https://ncbi.nlm.nih.gov/pubmed/18566040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.021352
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