Diminished immunogenicity of a recombination-deficient derivative of Vibrio cholerae vaccine strain CVD103.

To address potential concerns over the release of genetically engineered live bacterial vaccines, we constructed a recombination-deficient derivative of the Vibrio cholerae O1 vaccine strain CVD103 (CVD103RM). Oral immunization of adult volunteers with CVD103RM showed that the recA mutation signific...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ketley, J M, Kaper, J B, Herrington, D A, Losonsky, G, Levine, M M
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC258653/
https://ncbi.nlm.nih.gov/pubmed/2323828
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires