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Inhibiting the platelet derived growth factor receptor increases signs of retinoic acid syndrome in myeloid differentiated HL- 60 cells

PDGFR inhibitors are successfully used in a number of cancer treatments. The standard treatment for acute promyelocytic leukemia (APL) involves differentiation therapy with retinoic acid (RA). However, the relapse rates are significant. In the present work we evaluated the effects of RA therapy in t...

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Hlavní autoři: Reiterer, Gudrun, Bunaciu, Rodica P., Smith, James L., Yen, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585509/
https://ncbi.nlm.nih.gov/pubmed/18571505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.06.016
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