New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals

Neuronal pigments of melanic type were identified in the putamen, cortex, cerebellum, and other major regions of human brain. These pigments consist of granules 30 nm in size, contained in organelles together with lipid droplets, and they accumulate in aging, reaching concentrations as high as 1.5–2...

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Autori principali: Zecca, Luigi, Bellei, Chiara, Costi, Patrizia, Albertini, Alberto, Monzani, Enrico, Casella, Luigi, Gallorini, Mario, Bergamaschi, Luigi, Moscatelli, Alberto, Turro, Nicholas J., Eisner, Melvin, Crippa, Pier Raimondo, Ito, Shosuke, Wakamatsu, Kazumasa, Bush, William D., Ward, Weslyn C., Simon, John D., Zucca, Fabio A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582310/
https://ncbi.nlm.nih.gov/pubmed/18988735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808768105
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