New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals

Neuronal pigments of melanic type were identified in the putamen, cortex, cerebellum, and other major regions of human brain. These pigments consist of granules 30 nm in size, contained in organelles together with lipid droplets, and they accumulate in aging, reaching concentrations as high as 1.5–2...

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Detalhes bibliográficos
Main Authors: Zecca, Luigi, Bellei, Chiara, Costi, Patrizia, Albertini, Alberto, Monzani, Enrico, Casella, Luigi, Gallorini, Mario, Bergamaschi, Luigi, Moscatelli, Alberto, Turro, Nicholas J., Eisner, Melvin, Crippa, Pier Raimondo, Ito, Shosuke, Wakamatsu, Kazumasa, Bush, William D., Ward, Weslyn C., Simon, John D., Zucca, Fabio A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582310/
https://ncbi.nlm.nih.gov/pubmed/18988735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808768105
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