Llwytho...

Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids

The semi-invariant Vα14Jα18 T cell receptor (TCR) is expressed by regulatory NKT cells and has the unique ability to recognize chemically diverse ligands presented by CD1d. The crystal structure of CD1d complexed to a natural, endogenous ligand, isoglobotrihexosylceramide (iGb3), illustrates the ext...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zajonc, Dirk M., Savage, Paul B., Bendelac, Albert, Wilson, Ian A., Teyton, Luc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579742/
https://ncbi.nlm.nih.gov/pubmed/18295796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.061
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