The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals

The protein encoded by the PPARGC1A gene is expressed at high levels in metabolically active tissues and is involved in the control of oxidative stress via reactive oxygen species detoxification. Several recent reports suggest that the PPARGC1A Gly482Ser (rs8192678) missense polymorphism may relate...

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Main Authors: Vimaleswaran, Karani Santhanakrishnan, Luan, Jian'an, Andersen, Gitte, Muller, Y. Li, Wheeler, Eleanor, Brito, Ema C., O'Rahilly, Stephen, Pedersen, Oluf, Baier, Leslie J., Knowler, William C., Barroso, Inês, Wareham, Nicholas J., Loos, Ruth J. F., Franks, Paul W.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576025/
https://ncbi.nlm.nih.gov/pubmed/18467552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.90423.2008
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