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Impaired Dendritic Cell Function in Aging Leads to Defective Antitumor Immunity

We recently reported that bone marrow-derived dendritic cells (DCs) are less effective than their young counterparts in inducing the regression of B16-ovalbumin (OVA) melanomas. To examine the underlying mechanisms, we investigated the effect of aging on DC tumor antigen presentation and migration....

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Bibliografski detalji
Glavni autori: Grolleau-Julius, Annabelle, Harning, Erin K., Abernathy, Lisa M., Yung, Raymond L.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575813/
https://ncbi.nlm.nih.gov/pubmed/18676859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5769
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