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Impaired Dendritic Cell Function in Aging Leads to Defective Antitumor Immunity
We recently reported that bone marrow-derived dendritic cells (DCs) are less effective than their young counterparts in inducing the regression of B16-ovalbumin (OVA) melanomas. To examine the underlying mechanisms, we investigated the effect of aging on DC tumor antigen presentation and migration....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575813/ https://ncbi.nlm.nih.gov/pubmed/18676859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5769 |
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