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The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

The persistence of Mycobacterium tuberculosis despite prolonged chemotherapy represents a major obstacle for the control of tuberculosis. The mechanisms used by Mtb to persist in a quiescent state are largely unknown. Chemical genetic and genetic approaches were used here to study the physiology of...

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Autors principals: Rao, Srinivasa P. S., Alonso, Sylvie, Rand, Lucinda, Dick, Thomas, Pethe, Kevin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575262/
https://ncbi.nlm.nih.gov/pubmed/18697942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711697105
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