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Predicting In Vivo Efficacy of Potential Restenosis Therapies by Cell Culture Studies: Species-Dependent Susceptibility of Vascular Smooth Muscle Cells

Although drug-eluting stents (DES) are successfully utilized for restenosis therapy, the development of local and systemic therapeutic means including nanoparticles (NP) continues. Lack of correlation between in vitro and in vivo studies is one of the major drawbacks in developing new drug delivery...

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Main Authors: Hila, Epstein, Rabinovich, Laura, Banai, Shmuel, Elazar, Vicktoria, Gao, Jianchuan, Chorny, Michael, Danenebrg, Haim D, Golomb, Gershon
格式: Artigo
語言:Inglês
出版: Bentham Open 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570571/
https://ncbi.nlm.nih.gov/pubmed/18949101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874192400802010060
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