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Long Range Cooperative Interactions Modulate Dimerization in SARS 3CL(pro)
Severe acute respiratory syndrome (SARS) is an infectious disease caused by the human coronavirus, SARS-CoV. The main viral protease, SARS 3CL(pro) is a validated target for the development of antiviral therapies. Since the enzyme is a homodimer and the individual monomers are inactive, two approach...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570436/ https://ncbi.nlm.nih.gov/pubmed/17154528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0616302 |
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