Ecto-nucleoside Triphosphate Diphosphohydrolase 1 (E-NTPDase1/CD39) Regulates Neutrophil Chemotaxis by Hydrolyzing Released ATP to Adenosine

Polymorphonuclear neutrophils release ATP in response to stimulation by chemoattractants, such as the peptide N-formyl-methionyl-leucyl-phenylalanine. Released ATP and the hydrolytic product adenosine regulate chemotaxis of neutrophils by sequentially activating purinergic nucleotide and adenosine r...

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Autores principales: Corriden, Ross, Chen, Yu, Inoue, Yoshiaki, Beldi, Guido, Robson, Simon C., Insel, Paul A., Junger, Wolfgang G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568933/
https://ncbi.nlm.nih.gov/pubmed/18713747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800039200
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