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Role of αBI5 and αBT162 residues in subunit interaction during oligomerization of αB-crystallin

PURPOSE: To determine whether the residues in the NH(2)- and COOH-terminal extensions interact with one another during oligomerization of αB-crystallin. METHODS: Site-directed mutagenesis was used to mutate αBI5 and αBT162 residues to Cys. The recombinant I5C and T162C proteins were expressed in Esc...

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Autors principals: Murugesan, Raju, Santhoshkumar, Puttur, Sharma, K. Krishna
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568893/
https://ncbi.nlm.nih.gov/pubmed/18941542
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