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Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high‐density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function

BACKGROUND: Hereditary mixed polyposis syndrome (HMPS) is characterised by colonic polyps of mixed histological types that are autosomal dominantly inherited and eventually lead to colorectal cancer (CRC). Study of the molecular basis of HMPS will enhance our knowledge of the genetic basis of the mi...

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Detalles Bibliográficos
Main Authors: Cao, X, Eu, K W, Kumarasinghe, M P, Li, H H, Loi, C, Cheah, P Y
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563243/
https://ncbi.nlm.nih.gov/pubmed/16525031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.034827
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