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Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high‐density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function

BACKGROUND: Hereditary mixed polyposis syndrome (HMPS) is characterised by colonic polyps of mixed histological types that are autosomal dominantly inherited and eventually lead to colorectal cancer (CRC). Study of the molecular basis of HMPS will enhance our knowledge of the genetic basis of the mi...

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Bibliographische Detailangaben
Hauptverfasser: Cao, X, Eu, K W, Kumarasinghe, M P, Li, H H, Loi, C, Cheah, P Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563243/
https://ncbi.nlm.nih.gov/pubmed/16525031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.034827
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