A Combinatorial Approach to Detecting Gene-Gene and Gene-Environment Interactions in Family Studies

Widespread multifactor interactions present a significant challenge in determining risk factors of complex diseases. Several combinatorial approaches, such as the multifactor dimensionality reduction (MDR) method, have emerged as a promising tool for better detecting gene-gene (G × G) and gene-envir...

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Main Authors: Lou, Xiang-Yang, Chen, Guo-Bo, Yan, Lei, Ma, Jennie Z., Mangold, Jamie E., Zhu, Jun, Elston, Robert C., Li, Ming D.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561932/
https://ncbi.nlm.nih.gov/pubmed/18834969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.09.001
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