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Insulin Growth Factor-1 Gene Transfer Enhances Neurovascular Remodeling and Improves Long-Term Stroke Outcome in Mice

BACKGROUND AND PURPOSE: Insulin-like growth factor I (IGF-1) is a pleiotropic growth factor that has been demonstrated to protect against acute ischemic brain injury. Whether IGF-1 improves long-term functional outcome after ischemic stroke is not known. The aim of this study is to examine whether I...

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Autores principales: Zhu, Wei, Fan, Yongfeng, Frenzel, Tim, Gasmi, Mehdi, Bartus, Raymond T., Young, William L., Yang, Guo-Yuan, Chen, Yongmei
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553752/
https://ncbi.nlm.nih.gov/pubmed/18309153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.107.500801
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