DETANO and Nitrated Lipids Increase Chloride Secretion across Lung Airway Cells

We investigated the cellular mechanisms by which nitric oxide (NO) increases chloride (Cl(−)) secretion across lung epithelial cells in vitro and in vivo. Addition of (Z)-1-[2-(2-aminoethyl)-N-(2-ammonioethyl) amino] diazen-1-ium-1, 2-diolate (DETANONOate [DETANO];1–1,000 μM) into apical compartment...

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Main Authors: Chen, Lan, Bosworth, Charles A., Pico, Tristant, Collawn, James F., Varga, Karoly, Gao, Zhiqian, Clancy, John Paul, Fortenberry, James A., Lancaster, Jack R., Matalon, Sadis
格式: Artigo
語言:Inglês
出版: American Thoracic Society 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542453/
https://ncbi.nlm.nih.gov/pubmed/18314534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0005OC
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