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ANALYSIS OF 3-PHOSPHOINOSITIDE-DEPENDENT KINASE-1 SIGNALING AND FUNCTION IN ES CELLS

3-Phosphoinositide-dependent kinase-1 (PDK1) phosphorylates and activates several kinases in the cAMP-dependent, cGMP-dependent and protein kinase C(AGC) family. Many putative PDK1 substrates have been identified, but have not been analyzed following transient and specific inhibition of PDK1 activit...

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Autors principals: Tamgüney, Tanja, Zhang, Chao, Fiedler, Dorothea, Shokat, Kevan, Stokoe, David
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531073/
https://ncbi.nlm.nih.gov/pubmed/18514190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.04.006
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