A Dual Receptor Crosstalk Model of G-Protein-Coupled Signal Transduction

Macrophage cells that are stimulated by two different ligands that bind to G-protein-coupled receptors (GPCRs) usually respond as if the stimulus effects are additive, but for a minority of ligand combinations the response is synergistic. The G-protein-coupled receptor system integrates signaling cu...

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Главные авторы: Flaherty, Patrick, Radhakrishnan, Mala L., Dinh, Tuan, Rebres, Robert A., Roach, Tamara I., Jordan, Michael I., Arkin, Adam P.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2008
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528964/
https://ncbi.nlm.nih.gov/pubmed/18818727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000185
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