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Adverse effects of fullerenes on endothelial cells: Fullerenol C(60)(OH)(24) induced tissue factor and ICAM-1 membrane expression and apoptosis in vitro

We studied the effects of a C(60) water suspension at 4 μg/mL (nC(60)) and the water soluble fullerenol C(60)(OH)(24) at final concentrations of 1(–)100 μg/mL on human umbilical vein endothelial cells (HUVECs) in culture. We found that a 24 hr treatment of HUVECs with C(60)(OH)(24) at 100 μg/mL sign...

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Autores principales: Gelderman, Monique P, Simakova, Olga, Clogston, Jeffrey D, Patri, Anil K, Siddiqui, Sheena F, Vostal, Alexander C, Simak, Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527653/
https://ncbi.nlm.nih.gov/pubmed/18488416
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