Neuronal system-dependent facilitation of tumor angiogenesis and tumor growth by calcitonin gene-related peptide

A neuropeptide, calcitonin gene-related peptide (CGRP), is widely distributed in neuronal systems and exhibits numerous biological activities. Using CGRP-knockout mice (CGRP(−/−)), we examined whether or not endogenous CGRP facilitates angiogenesis indispensable to tumor growth. CGRP increased tube...

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Bibliographic Details
Main Authors: Toda, Masaya, Suzuki, Tatsunori, Hosono, Kanako, Hayashi, Izumi, Hashiba, Shinichiro, Onuma, Yuichiro, Amano, Hideki, Kurihara, Yukiko, Kurihara, Hiroki, Okamoto, Hirotsugu, Hoka, Sumio, Majima, Masataka
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527353/
https://ncbi.nlm.nih.gov/pubmed/18757746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800767105
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